Motif ID: MEF2{A,B,C,D}.p2

Z-value: 1.559


Transcription factors associated with MEF2{A,B,C,D}.p2:

Gene SymbolEntrez IDGene Name
MEF2A 4205 myocyte enhancer factor 2A
MEF2B 100271849 myocyte enhancer factor 2B
MEF2BNB-MEF2B 4207 MEF2BNB-MEF2B readthrough
MEF2C 4208 myocyte enhancer factor 2C
MEF2D 4209 myocyte enhancer factor 2D

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MEF2Cchr5_-_882147200.351.9e-01Click!
LOC729991-MEF2Bchr19_-_19163916-0.302.6e-01Click!
MEF2Achr15_+_97923737-0.224.1e-01Click!
MEF2Bchr19_-_191420900.214.4e-01Click!
MEF2Dchr1_-_1547371890.194.8e-01Click!


Activity profile for motif MEF2{A,B,C,D}.p2.

activity profile for motif MEF2{A,B,C,D}.p2


Sorted Z-values histogram for motif MEF2{A,B,C,D}.p2

Sorted Z-values for motif MEF2{A,B,C,D}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MEF2{A,B,C,D}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_69539255 1.958 NM_032578
MYPN
myopalladin
chr3_-_39209075 1.855 NM_194293
NM_001198621
XIRP1

xin actin-binding repeat containing 1

chr6_-_123999640 1.744 NM_006073
TRDN
triadin
chr5_+_155686333 1.633 NM_000337
NM_001128209
NM_172244
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr2_+_88148413 1.551 NM_198274
SMYD1
SET and MYND domain containing 1
chr8_+_40130143 1.450 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr2_-_190635566 1.324 NM_005259
MSTN
myostatin
chr3_+_42702014 1.095 NM_152393
KBTBD5
kelch repeat and BTB (POZ) domain containing 5
chr18_-_3209986 1.086 NM_003803
NM_019856
MYOM1

myomesin 1, 185kDa

chr6_+_27885692 1.063 NM_003536
HIST1H3H
histone cluster 1, H3h
chr2_+_204279442 1.060 NM_006139
CD28
CD28 molecule
chr7_-_113346284 1.049 NM_002711
PPP1R3A
protein phosphatase 1, regulatory (inhibitor) subunit 3A
chr5_-_83052606 1.021 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chr4_-_23500706 0.990 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr6_-_139654807 0.975 NM_153235
TXLNB
taxilin beta
chr6_+_26266311 0.964 NM_021063
NM_138720
HIST1H2BD

histone cluster 1, H2bd

chr22_+_24468168 0.951 MYO18B
myosin XVIIIB
chr2_-_69033515 0.940 NM_182536
GKN2
gastrokine 2
chr10_-_62373828 0.931 NM_014836
RHOBTB1
Rho-related BTB domain containing 1
chr12_-_55931172 0.911 NM_145064
STAC3
SH3 and cysteine rich domain 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
4.66 3.67e-03 GO:0030049 muscle filament sliding
4.66 3.67e-03 GO:0033275 actin-myosin filament sliding
4.53 5.19e-03 GO:0070252 actin-mediated cell contraction
3.64 3.89e-02 GO:0030048 actin filament-based movement
2.47 3.73e-03 GO:0003012 muscle system process
2.05 2.56e-02 GO:0061061 muscle structure development

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
9.46 1.66e-02 GO:0005577 fibrinogen complex
4.06 5.08e-09 GO:0030017 sarcomere
3.88 8.84e-10 GO:0030016 myofibril
3.87 2.76e-03 GO:0031674 I band
3.84 2.84e-02 GO:0030018 Z disc
3.75 1.07e-08 GO:0044449 contractile fiber part
3.66 5.43e-09 GO:0043292 contractile fiber
3.42 3.59e-03 GO:0000786 nucleosome
1.50 3.78e-02 GO:0005615 extracellular space
1.49 3.86e-03 GO:0044421 extracellular region part
1.34 2.64e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
4.97 2.03e-02 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor